589 research outputs found

    Light scattering from a rough metal surface: theory and experiment

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    There is still great interest in the determination of microtopographic properties of rough metallic surfaces from light scattering measurements. According to Beckmann–Kirchhoff theory a clear relationship is established between the in-plane angular scattered light intensity and the statistical properties of the surface. We discuss one way to invert this relationship, and we introduce a new iterative procedure to retrieve the height autocorrelation function even for a very rough metallic surface (rms surface roughness of the same order of the optical wavelength). The procedure is eventually applied to the experimental data of a known metallic surface for validation

    Quantum properties of optical field in photonic band gap structures.

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    A theoretical analysis of the quantum behaviour of radiation field's propagation in photonic band gaps structures is performed. In these initial calculations we consider linear inhomogeneous and nondispersive media

    The ghrelin paradox in the control of equine chondrocyte function: The good and the bad

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    Increasing evidence suggests a role for ghrelin in the control of articular inflammatory diseases like osteoarthritis (OA). In the present study we examined the ability of ghrelin to counteract LPS-induced necrosis and apoptosis of chondrocytes and the involvement of GH secretagogue receptor (GHS-R)1a in the protective action of ghrelin. The effects of ghrelin (10-7-10-11\u202fmol/L) on equine primary cultured chondrocytes viability and necrosis in basal conditions and under LPS treatment (100\u202fng/ml) were detected by using both acridine orange/propidium iodide staining and annexin-5/propidium iodide staining. The presence of GHS-R1a on chondrocytes was detected by Western Blot. The involvement of the GHS-R1a in the ghrelin effect against LPS-induced cytotoxicity was examined by pretreating chondrocytes with D-Lys3-GHRP-6, a specific GHS-R1a antagonist, and by using des-acyl ghrelin (DAG, 10-7and 10-9\u202fmol/L) which did not recognize the GHS-R 1a. Low ghrelin concentrations reduced chondrocyte viability whereas 10-7\u202fmol/L ghrelin protects against LPS-induced cellular damage. The protective effect of ghrelin depends on the interaction with the GHS-R1a since it is significantly reduced by D-Lys3-GHRP-6. The negative action of ghrelin involves caspase activation and could be due to an interaction with a GHS-R type different from the GHS-R1a recognized by both low ghrelin concentrations and DAG. DAG, in fact, induces a dose-dependent decrease in chondrocyte viability and exacerbates LPS-induced damage. These data indicate that ghrelin protects chondrocytes against LPS-induced damage via interaction with GHS-R1a and suggest the potential utility of local GHS-R1a agonist administration to treat articular inflammatory diseases such as OA

    Classical and Quantum Approach of Quasi Normal Modes in Linear Optical Regime: An Application to One Dimensional Photonic Crystals

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    The definition of natural modes for confined structures is one of the central problems in physics, as in nuclear physics, astrophysics, etc. The main problem is due to the boundary conditions, when they are such to push out the problem from the class of Sturm-Liouville. This occurs when boundary conditions imply the presence of eigen-values, as for example when a scatterer excited from the outside gives rise to a transmitted and reflected field. An open cavity with an external or internal excitation represents a "non-canonical" problem, in the sense of a Sturm-Liouville's problem, due to the fact that cavity modes couple themselves with external modes. This problem is crucial when one intends to study light-matter interaction effects as absorption, spontaneous emission, stimulated emission, as they occur in micro-cavities.Comment: Ph-D Thesis in Electromagnetism: Settimi et al., Phys. Rev. E 68, 026614 [11 pages] (2003); Severini et al., Acta Phys. Hung. B 23/3-4, 135-142 (2005); Severini et al., Phys. Rev. E, 70, 056614 [12 pages](2004); Severini et al., Laser Physics, 16, 911-920 (2006); Settimi et al., Phys. Rev. E 71, 066606 [10 pages] (2005); Settimi et al., Eur. Phys. J. B. 50, 379-391 (2006

    Electro-Thermal Parameters of Graphene Nano-Platelets Films for De-Icing Applications

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    This paper provides a study of some relevant electro-thermal properties of commercial films made by pressed graphene nano-platelets (GNPs), in view of their use as heating elements in innovative de-icing systems for aerospace applications. The equivalent electrical resistivity and thermal emissivity were studied, by means of models and experimental characterization. Macroscopic strips with a length on the order of tens of centimeters were analyzed, either made by pure GNPs or by composite mixtures of GNPs and a small percentage of polymeric binders. Analytical models are derived and experimentally validated. The thermal response of these graphene films when acting as a heating element is studied and discussed

    Electrical impedance spectroscopy for real-time monitoring of the life cycle of graphene nanoplatelets filters for some organic industrial pollutants

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    This article proposes an approach for smart monitoring of the life cycle of innovative graphene-haled filters for water remediation in the presence of pollutants. The measurement technique is based on suitable figures of merit that analyze the time variation of the electrical impedance frequency spectrum. The proposed study considers the remediation of two toxic industrial pollutants, such as the acetonitrile and the 2,4-dichlorophenol. The contribution of this article is twofold. The first is the demonstration of a reliable monitoring setup that is able, for the selected use cases, to correlate in real time the behavior of the electrical impedance of the filter to its status, defined as "absence of pollutants" and/or "saturation." The second contribution is the proposal of suitable figures of merit, based on measurement of the impedance frequency spectrum, able to increase the measurement sensitivity and the reliability and to mitigate some sources of uncertainty typically associated with these kinds of setups and measurements. Results show that the proposed graphene-based filters combine very good filtering capability and high sensitivity of the electrical impedance to the considered pollutants. These results suggest further investigations with other pollutants and the potential use of this technique for the predictive maintenance of the water filters in industrial applications, by endowing the graphene filters of smart sensing devices

    Moderate inappropriately high aldosterone/NaCl constellation in mice: cardiovascular effects and the role of cardiovascular epidermal growth factor receptor

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    Non-physiological activation of the mineralocorticoid receptor (MR), e.g. by aldosterone under conditions of high salt intake, contributes to the pathogenesis of cardiovascular diseases, although beneficial effects of aldosterone also have been described. The epidermal growth factor receptor (EGFR) contributes to cardiovascular alterations and mediates part of the MR effects. Recently, we showed that EGFR is required for physiological homeostasis and function of heart and arteries in adult animals. We hypothesize that moderate high aldosterone/NaCl, at normal blood pressure, affects the cardiovascular system depending on cardiovascular EGFR. Therefore we performed an experimental series in male and female animals each, using a recently established mouse model with EGFR knockout in vascular smooth muscle cells and cardiomyocytes and determined the effects of a mild-high aldosterone-to-NaCl constellation on a.o. marker gene expression, heart size, systolic blood pressure, impulse conduction and heart rate. Our data show that (i) cardiac tissue of male but not of female mice is sensitive to mild aldosterone/NaCl treatment, (ii) EGFR knockout induces stronger cardiac disturbances in male as compared to female animals and (iii) mild aldosterone/NaCl treatment requires the EGFR in order to disturb cardiac tissue homeostasis whereas beneficial effects of aldosterone seem to be independent of EGFR
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